Comprehensive support for the nervous system
Highly absorbable forms of B1, B2, B6
Tested microbiologically, for heavy metals and ethylene oxide
Servings per container: Vitamin B1: 60, Vitamin B2: 60, Vitamin B6: 60
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Thiamine pyrophosphate (coenzymated cocarboxylase) is a coenzyme of pyruvate dehydrogenase, alpha-ketoglucarate and transketolase.
The first two enzymes are important for pyruvate metabolism in the Krebs cycle and are the basis for energy production from food.
Thanks to transketolase, NADPH is produced, which is involved, among others, in the production of fatty acids and steroid hormones; it is also a component used in the synthesis of nucleic acids, and electron carriers (necessary for the production of ATP; NAD+, FAD).
Pyrophosphate is also highly concentrated in the cells of the nervous system and muscles as being essential for the production of nerve impulses and conscious muscle movement.
The coenzymated form of vitamin B1 is a biologically active form of vitamin B₁, being one of the most absorbable forms of vitamin B1.
Vitamins monographs – Huntington University of Health Sciences
Riboflavin is the primary form of the vitamin that the human intestine can absorb, and in the body, it is converted to active coenzyme forms. Riboflavin 5′-Phosphate is metabolised to the free form of Riboflavin by alkaline phosphatase in the small intestine.
B2 is the vitamin absorbed both as the free form of riboflavin and as the flavin mononucleotide or R-5′-P. Absorption is better when the vitamin is taken after a meal because the gastric contents slow down peristalsis and prolong the vitamin gastric residence time, which promotes its efficient uptake.
Pyridoxal 5-Phosphate, or P-5-P, is the active form of Vitamin B6. The difference between regular Pyridoxine and P-5-P is that P-5-P does not need to undergo any more transformations as it is the target form of Vitamin B6.
Pyridoxal 5-Phosphate plays the role of a coenzyme or prosthetic group. It is crucial for the function of many enzymes responsible for amino acid metabolism (aminotransferases and decarboxylases).
Thiamine or Vitamin B1, Riboflavin or Vitamin B2 and Pyridoxine or Vitamin B6 can be taken together.