Name: Magnesium L-Threonate Magtein®
SKU: 301-2
Availability: InStock

Product description

Magnesium L-Threonate Magtein® dietary supplement contains magnesium in the form of magnesium threonate, enclosed in a vegan capsule. Magnesium threonate is a form of magnesium that effectively crosses the blood-brain barrier.

Magnesium is an essential and irreplaceable component of the cell’s biochemical functions, which activates more than 300 different enzymes. It is actively involved in important metabolic pathways such as glycolysis, the Krebs cycle, β-oxidation and ion transport across cell membranes. Given its physicochemical properties, Mg2 can bind to the cell nucleus, ribosomes, cell membranes and macromolecules of the cell cytosol.

Magnesium L-Threonate:

improves working memory, executive functions, and overall cognitive performance,
enhances sleep quality – increases the duration of deep sleep and REM phase, supports daily functioning,
reduces stress and anxiety levels,
may support the nervous system in anxiety-related responses
may have a neuroprotective effect by raising magnesium levels in the brain, relevant in preventing neurodegenerative diseases,
influences neurotransmission (NMDA, GABA, glutamate).

Magnesium:

helps maintain normal nervous system function,
contributes to the reduction of feelings of tiredness and fatigue,
helps maintain electrolyte balance,
helps maintain normal energy metabolism,
helps in normal muscle function,
supports normal protein synthesis,
helps maintain normal psychological functions,
helps maintain healthy bones,
helps maintain healthy teeth,
plays a role in cell division.

Liu G, Weinger JG, Lu ZL, Xue F, Sadeghpour S. “Efficacy and Safety of MMFS-01, a Synapse Density Enhancer, for Treating Cognitive Impairment in Older Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.” J Alzheimer’s Dis. 2016;49:971-990.

Hausenblas H, Lynch T, Hooper S, Shrestha A, Rosendale D, Gu J. “Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.” Sleep Medicine: X. August 17, 2024.

Zhang C, Hu Q, Li S, Dai F, Qian W, Hewlings S, Yan T, Wang Y. “A Magtein, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults.” Nutrients. 2022; 14(24):5235.

Hewlings SJ, Kalman DS. “A Randomized, Double-Blind, Placebo-Controlled, Comparator Trial Evaluating Magtein® Magnesium Supplement on Quality of Life as Related to Levels of Stress, Anxiety, Fear and Other Indicators.” EC Nutrition 17.3 (2022): 07-14.

Supplement facts

Ingredient	Amount per daily serving 3 capsules
Magnesium L-Threonate	2000 mg	–
– Magnesium	144 mg	38% DV*

*DV – Daily Value.

Ingredients: Magnesium L-Threonate, Pullulan – Vegan Capsule Shell.

Gluten-free.

Amount per container: 90 vegan capsules.

Servings per container: 30.

Suggested use

Take 3 capsules daily.

The capsule contents can be emptied and dissolved in water. Magnesium L-Threonate Magtein® supplement dissolves completely in water and is tasteless.

Do not exceed suggested use. Dietary supplements should not replace a varied diet. The product is recommended for adults.

Warning: if pregnant or nursing, consult your doctor before use.

Organoleptic properties: when emptied from the capsule, a white, nearly tasteless powder. It dissolves completely in water. Due to the molecular weight of magnesium threonate and its high level of dusting, a slight residue from the capsules may remain at the bottom of the container.

Keep away from the sun at a temperature below 25°C in the original packaging, out of reach of small children.

Production lot number / Best before – see the unit label (left side of the label).

Tests

Batch tests performed towards:

Microbiology: the presence of listeria, staphylococcus, Escherichia coli and coli groups, salmonella, total microbial count,
heavy metals (arsenic, cadmium, lead, mercury),
ethylene oxide and 2-chloroethanol,
gluten content.

The tests were carried out at the independent, accredited Laboratorium Hamilton Polska.

Tests PDF

Magtein® - discover the unique benefits of Magnesium L-Threonate

Magtein® (magnesium L-threonate) supplementation increases magnesium levels in the brain, which supports improvements in learning ability, working memory, and short- and long-term memory.

Clinical research has shown that 12 weeks of Magtein® supplementation can enhance synaptic density and improve cognitive function in older adults. This effect is linked to improved synaptic plasticity in the hippocampus – a key area for learning and memory processes.

Yes, Magtein® has been shown to help reduce stress and anxiety.

A clinical study by Hewlings & Kalman (2022) in adults aged 50-70 demonstrated that 12 weeks of supplementation significantly lowered anxiety and stress levels on the Hamilton Anxiety Rating Scale (HAM-A) compared to placebo.

The effect is linked to magnesium’s influence on neurotransmitters such as serotonin and dopamine, as well as its role in regulating the HPA axis (hypothalamic-pituitary-adrenal axis) – the body’s main stress-response system.

In stressful situations, the hypothalamus releases CRH, which stimulates the pituitary to produce ACTH, triggering the adrenal glands to release cortisol (the stress hormone).
While cortisol helps the body cope short-term, chronic stress can overload and dysregulate the HPA axis, leading to fatigue, sleep disturbances, lowered immunity, and mood disorders.
Magnesium deficiency may contribute to excessive HPA axis activation, amplifying stress responses.

Research shows that Magtein® supplementation improves sleep quality and daytime functioning.

In a study by Hausenblas et al. (2024), participants taking Magtein® experienced better sleep quality, fewer nighttime awakenings, and greater daytime recovery.

The mechanism is linked to neurotransmitter modulation:

Magnesium helps reduce excessive activation of NMDA (glutamate) receptors, lowering neural excitability.
At the same time, it supports GABA activity, the main inhibitory neurotransmitter responsible for calmness, relaxation, and falling asleep.

Studies have shown that Magtein® benefits cognitive function across different age groups.

In a study by Zhang et al. (2022) involving 109 healthy adults, supplementation led to improved memory and faster information processing. While positive effects were observed in all participants, the greatest benefits appeared in older adults.

This may be due to the natural decline of brain magnesium levels with age, making older individuals more responsive to supplementation. At the same time, early use of magnesium supplementation may act preventively, helping maintain optimal magnesium levels in the brain and slowing age-related cognitive decline.