Homocysteine support - LABS212® - Suplementy diety

Dietary supplement

Homocysteine support

  • Comprehensive support of homocysteine metabolism

  • Support for methylation processes

  • Contains 3 active forms of vitamin B12: adenosylcobalamin, hydroxocobalamin, and methylcobalamin

  • Tested microbiologically, for heavy metals and ethylene oxide

  • Servings per container: 90

99.99 zł

991 in stock

Price per piece: 1,11 zł

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Support for homocysteine metabolism

Homocysteine is a sulfur-containing amino acid that is produced in the body as an intermediate product of methionine metabolism—an amino acid supplied through the diet. Under normal methylation processes, homocysteine does not accumulate in the body but is continuously converted into other compounds, primarily methionine. These mechanisms, however, require adequate availability of key nutrients.

Elevated homocysteine levels are considered a risk factor for the cardiovascular system, as they may negatively affect the vascular endothelium and contribute to impaired blood vessel function. Excessively high homocysteine concentrations are also associated with impaired nervous system function, cognitive processes, and increased oxidative stress.

Homocysteine is closely linked to methylation processes, which are essential for proper cellular function, neurotransmitter synthesis, regulation of gene expression, and detoxification. Elevated homocysteine levels may indicate reduced efficiency of these processes.

Maintaining normal homocysteine levels is an important element of preventive healthcare. Proper homocysteine levels support not only the heart and blood vessels, but also the nervous system, cellular metabolism, and overall biochemical balance of the body.

Elevated homocysteine levels most commonly result from disturbances in methylation processes—biochemical mechanisms responsible for converting homocysteine into other compounds that are safe for the body. For these processes to function properly, an adequate supply of specific nutrients is required, particularly vitamin B12, choline, and betaine (TMG). Deficiencies in these nutrients may lead to the accumulation of homocysteine in the blood.

Dietary factors also play a significant role. Insufficient intake of foods rich in B vitamins, high-quality protein, and natural sources of choline may impair homocysteine metabolism. This is especially relevant in the case of elimination diets, low-protein diets, or diets low in animal-derived products.

In a formulation aimed at supporting the maintenance of normal homocysteine levels, the efficiency and continuity of methylation processes are of key importance. The use of three forms of vitamin B-12 allows for comprehensive support of homocysteine metabolism and better alignment of the supplement’s action with the body’s physiological needs.

Methylcobalamin plays a direct role in the remethylation of homocysteine to methionine. As a biologically active form of vitamin B-12, it participates in key methylation reactions that are essential for maintaining normal homocysteine levels.

Hydroxocobalamin, as a natural and storage-capable form of vitamin B-12, provides long-term and stable support for the body. Thanks to its ability to convert into active B-12 forms, it helps ensure a continuous availability of the vitamin necessary for proper homocysteine metabolism.

Adenosylcobalamin supports mitochondrial function and cellular energy production, which indirectly influences the efficiency of metabolic processes, including methylation.

The combination of three forms of vitamin B-12 enables multidirectional, physiological support for the regulation of homocysteine levels, while also supporting the nervous system, energy metabolism, and overall metabolic balance of the body.

Vitamins B9 and B2 play key, complementary roles in methylation processes. Their presence increases the effectiveness of the formula and supports the body’s physiological mechanisms regulating homocysteine levels.

Vitamin B9 (active folate) plays a direct role in the remethylation of homocysteine to methionine. It participates in the folate cycle, which is responsible for the proper transfer of one-carbon units required to reduce homocysteine levels and maintain the body’s metabolic balance.

Vitamin B2 (riboflavin) acts as an essential cofactor for enzymes involved in the folate cycle. It supports the activation and efficient utilisation of vitamin B9, thereby indirectly influencing the efficiency of methylation processes.

The presence of vitamin B2 improves the performance of the entire methylation pathway, enhancing the effectiveness of actions aimed at regulating homocysteine levels.

The combination of vitamins B9 and B2 provides coherent and systemic support for homocysteine metabolism, while also supporting cell division processes, nervous system function, and overall metabolic balance of the body.

Choline and betaine (TMG) are included in the formulation due to their key role as methyl group donors in homocysteine metabolism. Both ingredients support an alternative, folate-independent remethylation pathway of homocysteine, which increases the effectiveness and flexibility of the formula.

Choline, after being converted into betaine (TMG), participates in the enzymatic remethylation of homocysteine to methionine. In this way, it supports the maintenance of normal homocysteine levels, particularly in situations of increased demand for methyl groups or reduced efficiency of other methylation pathways.

Betaine (TMG) acts as a direct methyl group donor and plays a central role in lowering homocysteine levels through the activation of betaine–homocysteine methyltransferase (BHMT). This mechanism is especially important in the liver, where a significant proportion of homocysteine metabolism takes place.

Choline also supports normal liver function and fat metabolism, which is important for overall metabolic balance and the efficiency of methylation processes.

The combination of choline and betaine (TMG) provides comprehensive support for homocysteine regulation, complementing the action of B vitamins and enhancing the overall effectiveness of the formula.

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